| The CASH BOX Rhythm & Blues Top 50 | ||||||
| Week ending DECEMBER 26, 1959 | ||||||
| TW | TITLE | Artist (Label) | LW | 2WK | 3WK | WKS | |
| 1 | SMOKIE (pt. 2) Bill Black’s Combo (Hi 2018) | 5 | 10 | 15 | 7 | |
| 2 | SO MANY WAYS Brook Benton (Mercury 71512) | 1 | 1 | 1 | 12 | |
| 3 | THE CLOUDS Spacemen (Alton 254) | 2 | 3 | 6 | 13 | |
| 4 | BE MY GUEST Fats Domino (Imperial 5629) | 3 | 4 | 4 | 9 | |
| 5 | DANCE WITH ME Drifters (Atlantic 2040) | 4 | 2 | 2 | 11 | |
| 6 | COME INTO MY HEART Lloyd Price (ABC-Paramount 10062) | 7 | 9 | 10 | 8 | |
| 7 | I’LL TAKE CARE OF YOU Bobby Bland (Duke 314) | 11 | 18 | 28 | 5 | |
| 8 | THE BIG HURT Miss Toni Fisher (Signet 275) | 22 | 27 | 36 | 4 | |
| 9 | TALK THAT TALK Jackie Wilson (Brunswick 55165) | 10 | 14 | 18 | 6 | |
| 10 | YOU GOT WHAT IT TAKES Marv Johnson (United Artists 185) | 13 | 19 | 25 | 8 | |
| 11 | UNFORGETTABLE Dinah Washington (Mercury 71508) | 9 | 7 | 5 | 13 | |
| 12 | I BELIEVE TO MY SOUL Ray Charles & Orchestra (Atlantic 2043) | 12 | 13 | 13 | 8 | |
| 13 | I’M MOVIN’ ON Ray Charles & Orchestra (Atlantic 2043) | 6 | 5 | 7 | 9 | |
| 14 | ALWAYS Sammy Turner (Big Top 3029) | 8 | 8 | 9 | 9 | |
| 15 | UH! OH! Nutty Squirrels (Hanover 4540) | 17 | 23 | 30 | 6 | |
| 16 | SMOOTH OPERATOR Sarah Vaughan (Mercury 71519) | 15 | 16 | 20 | 8 | |
| 17 | DON’T YOU KNOW Della Reese (RCA Victor 47-7591) | 14 | 6 | 3 | 14 | |
| 18 | FANNIE MAE Buster Brown (Fire 1008) | 26 | 46 | — | 3 | |
| 19 | LET THEM TALK Little Willie John (King 5274) | 21 | 28 | 29 | 7 | |
| 20 | MACK THE KNIFE Bobby Darin (Atco 6147) | 19 | 12 | 8 | 17 | |
| 21 | OH! CAROL Neil Sedaka (RCA Victor 47-7595) | 18 | 20 | 23 | 9 | |
| 22 | WE GOT LOVE Bobby Rydell (Cameo 169) | 24 | 30 | 32 | 5 | |
| 23 | SHADOWS 5 Satins (Ember 1056) | 20 | 21 | 22 | 11 | |
| 24 | (If You Cry) TRUE LOVE, TRUE LOVE Drifters (Atlantic 2040) | 16 | 11 | 11 | 10 | |
| 25 | WHAT ABOUT US Coasters (Atco 6153) | 27 | 41 | — | 3 | |
| 26 | WHY Frankie Avalon (Chancellor 1045) | 30 | 39 | 44 | 4 | |
| 27 | BABY WHAT YOU WANT ME TO DO Jimmy Reed (Vee-Jay 333) | 28 | 43 | — | 3 | |
| 28 | WAY DOWN YONDER IN NEW ORLEANS Freddy Cannon (Swan 4043) | 29 | 35 | 42 | 4 | |
| 29 | WONT’CHA COME HOME Lloyd Price (ABC-Paramount 10062) | 23 | 15 | 21 | 8 | |
| 30 | I CRIED LIKE A BABY Nappy Brown (Savoy 1575) | 25 | 22 | 24 | 8 | |
| 31 | I DON’T KNOW Ruth Brown (Atlantic 2035) | 32 | 33 | 19 | 15 | |
| 32 | IT’S TIME TO CRY Paul Anka (ABC-Paramount 10064) | 38 | 42 | 47 | 4 | |
| 33 | EBB TIDE Bobby Freeman (Josie 872) | 34 | 37 | 45 | 4 | |
| 34 | ROOSTER BLUES Lightnin’ Slim (Excello 2169) | 37 | 40 | 41 | 4 | |
| 35 | SHIMMY, SHIMMY, KO-KO-BOP Little Anthony & Imperials (End 1060) | 41 | 47 | — | 3 | |
| 36 | TEAR DROP Santo & Johnny (Canadian-American 107) | 39 | 49 | — | 3 | |
| 37 | IN THE MOOD Ernie Fields Orchestra (Rendezvous 110) | 31 | 17 | 16 | 11 | |
| 38 | LOVE POTION NO. 9 Clovers (United Artists 180) | 33 | 24 | 12 | 14 | |
| 39 | MR. BLUE Fleetwoods (Dolton 5) | 36 | 25 | 14 | 15 | |
| 40 | SAY MAN, BACK AGAIN Bo Diddley (Checker 936) | 35 | 31 | 33 | 5 | |
| 41 | HOW ABOUT THAT Dee Clark (Abner 1032) | 44 | — | — | 2 | |
| 42 | PRETTY BLUE EYES Steve Lawrence (ABC-Paramount 10058) | — | — | — | 1 | |
| 43 | GO, JIMMY, GO Jimmy Clanton (Ace 575) | 47 | — | — | 2 | |
| 44 | RUN RED RUN Coasters (Atco 6153) | 46 | 48 | — | 3 | |
| 45 | LOCK ME IN YOUR HEART (And Throw Away The Key) Tarheel Slim & Little Ann (Fire 1009) | — | — | — | 1 | |
| 46 | WE TOLD YOU NOT TO MARRY Titus Turner (Glover 201) | 43 | 36 | 37 | 6 | |
| 47 | BELIEVE ME Royal Teens (Capitol 4261) | 45 | 38 | 43 | 4 | |
| 48 | JUST TO BE WITH YOU Passions (Audicon 102) | 48 | 50 | — | 3 | |
| 49 | I’VE BEEN AROUND Fats Domino (Imperial 5629) | 40 | 26 | 26 | 8 | |
| 50 | REVEILLE ROCK Johnny & The Hurricanes (Warwick 513) | 42 | 34 | 35 | 6 | |
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